Table 2.
Results of Multivariate Logistic Regression Analysis for Baseline Covariates for the Prediction of In-Hospital Mortality for Patients With Sepsis.a
| Variable | Odds Ratio | Confidence Interval (95%) | Adjusted Odds Ratio | Confidence Interval (95%) | P |
|---|---|---|---|---|---|
| Older age, per 5-year increase | – | – | 1.08 | 1.07–1.09 | <.01 |
| Female gender | 0.87 | 0.85–0.89 | 0.93 | 0.91–0.94 | <.01 |
| White race | 0.99 | 0.95–1.03 | – | – | – |
| Black race | 1.02 | 0.96–1.07 | 1.08 | 1.05–1.11 | <.01 |
| Hispanic race | 1.01 | 0.95–1.07 | 1.03 | 0.99–1.06 | .09 |
| Other race | 0.99 | 0.93–1.06 | 1.15 | 1.12–1.18 | <.01 |
| Zip code income quartile 1 | 1.01 | 0.97–1.05 | 1.06 | 1.03–1.08 | <.01 |
| Zip code income quartile 2 | 0.97 | 0.93–0.99 | 1.02 | 0.99–1.05 | .14 |
| Zip code income quartile 3 | 0.96 | 0.93–0.99 | 0.99 | 0.97–1.01 | .40 |
| Zip code income quartile 4 | 1.06 | 1.01–1.10 | – | – | – |
| Small hospital | 0.99 | 0.91–1.08 | – | – | – |
| Medium hospital | 0.95 | 0.88–1.01 | 0.88 | 0.86–0.91 | <.01 |
| Large hospital | 1.04 | 0.98–1.10 | 0.95 | 0.93–0.98 | <.01 |
| Teaching hospital | 1.09 | 1.02–1.16 | 1.05 | 1.03–1.07 | <.01 |
| Insurance coverage | 1.00 | 0.93–1.07 | 0.78 | 0.75–0.81 | <.01 |
| Shock | 2.73 | 2.64–2.83 | 2.53 | 2.49–2.58 | <.01 |
| ICU admission | 3.40 | 3.20–3.60 | 4.10 | 3.90–4.32 | <.01 |
| Early mechanical ventilation | 3.76 | 3.64–3.90 | 1.01 | 0.96–1.07 | .68 |
| Do not resuscitate status | 4.82 | 4.53–5.13 | 4.24 | 4.15–4.34 | <.01 |
| Alcohol abuse | 1.05 | 1.01–1.10 | 0.87 | 0.84–0.91 | <.01 |
| Anemia | 0.50 | 0.48–0.53 | 0.55 | 0.53–0.58 | <.01 |
| Arthritis | 0.86 | 0.82–0.90 | 1.05 | 1.01–1.10 | .02 |
| Congestive heart failure | 1.36 | 1.32–1.39 | 1.39 | 1.36–1.42 | <.01 |
| Chronic lung disease | 1.00 | 0.97–1.02 | 0.93 | 0.91–0.95 | <.01 |
| Depression | 0.57 | 0.55–0.60 | 0.67 | 0.65–0.69 | <.01 |
| Diabetes | 0.72 | 0.70–0.74 | 0.82 | 0.81–0.84 | <.01 |
| Drug abuse | 0.52 | 0.48–0.56 | 0.58 | 0.55–0.61 | <.01 |
| HIV infection | 1.26 | 1.09–1.45 | 1.46 | 1.33–1.61 | <.01 |
| Hypertension | 0.82 | 0.80–0.84 | 0.82 | 0.80–0.85 | <.01 |
| Hypothyroid | 0.80 | 0.77–0.82 | 0.81 | 0.79–0.83 | <.01 |
| Liver disease | 2.17 | 2.10–2.24 | 2.48 | 2.42–2.55 | <.01 |
| Lymphoma | 1.74 | 1.66–1.82 | 1.93 | 1.84–2.03 | <.01 |
| Metastatic cancer | 2.55 | 2.46–2.65 | 1.94 | 1.86–2.01 | <.01 |
| Nonmetastatic cancer | 2.04 | 1.98–2.10 | 1.48 | 1.44–1.53 | <.01 |
| Neurological disorders | 1.51 | 1.46–1.55 | 1.35 | 1.33–1.38 | <.01 |
| Obesity | 0.61 | 0.58–0.63 | 0.81 | 0.78–0.83 | <.01 |
| Paralysis | 1.02 | 0.97–1.07 | 0.98 | 0.93–1.02 | .29 |
| Peripheral vascular disease | 1.15 | 1.11–1.19 | 1.22 | 1.19–1.26 | <.01 |
| Peptic ulcer | 0.77 | 0.71–0.83 | 0.76 | 0.71–0.85 | <.01 |
| Psychiatric disease | 0.57 | 0.53–0.61 | 0.66 | 0.62–0.70 | <.01 |
| Pulmonary circulatory disease | 1.32 | 1.28–1.37 | 1.34 | 1.30–1.38 | <.01 |
| Renal failure | 0.89 | 0.87–0.91 | 1.12 | 1.09–1.16 | <.01 |
| Weight loss | 1.80 | 1.74–1.87 | 1.38 | 1.36–1.41 | <.01 |
Abbreviation: ICU, intensive care unit.
a
For race analysis, white is the reference. For zip code income quartile, the highest quartile serves as the reference. For hospital size, small hospitals serve as the reference. All variables displayed in the table were included in the final logistic regression model.