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Hydrogen peroxide formation induced by mito-metformin10 in PDACs. (A) Chemical scheme of H2O2-dependent oxidation of the o-MitoPhB(OH)2 probe. (B) Intracellular levels of o-MitoPhB(OH)2 (left panel) and o-MitoPhOH (right panel) in MiaPaCa-2 pancreatic cancer cells treated for 24 h with Mito-Met10.
