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. 2017 Nov 9;7:15134. doi: 10.1038/s41598-017-15420-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Short-term resistance exercise is associated with large-scale transcriptional remodelling in skeletal muscle in the presence of HFD. Venn diagrams representing the number of genes that were up-regulated (A) and down-regulated (B) in Sed-HFD and Ex-HFD group (excludes CHAC1 gene, which was upregulated in Ex-HFD and downregulated in Sed-HFD). The intersection represents the genes that were regulated following both interventions. Gene ontology analysis of genes that were up-regulated (C) and down-regulated (D) exclusively in the Ex-HFD group. FDR < 0.1 is shown by the dotted line.