Fig. 4.

Airway surface liquid pH in airway epithelial cells cultures. a No difference (p > 0.99) in ASL pH between CF (n = 5) and non-CF (n = 5) epithelial cell cultures measured using fibre-optic probes. The Mann–Whitney U-test was used for statistical analysis. Bars represent median (range). Each of the points represents a different patient (genotypes of CF cultures described in Supplementary Fig. 8). b No difference (p = 0.12) in ASL pH between CF (n = 15) and non-CF (n = 12) primary bronchial airway epithelial cell cultures using a conventional (potentiometric sensor) micro-pH probe was found using an unpaired t-test. Each of the points represents a different patient (cells harvested from excised CF lung transplant recipient lungs). Bars represent mean ± s.d.