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. 2017 Nov 9;7:15140. doi: 10.1038/s41598-017-15474-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ROS scavenging with NAC reduces cell migration under hypoxic conditions. MDA-MB-468 cells were treated with NAC and exposed to hypoxia. Cell migration was analysed from 24 h to 36 h under hypoxic conditions. (A) Spatial plot of all cells from representative wells from the same experiment and (B) quantitative analysis of the mean accumulated distance travelled by cells from three independent experiment (duplicate wells) treated with NAC compared to the control cells without NAC treatment. *p < 0.05, (paired t-test).