Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 9;7:15130. doi: 10.1038/s41598-017-15417-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Ex vivo biodistribution profile of radiolabelled 4hD29 and control nanobodies in mice implanted with a Kelly neuroblastoma subcutaneous tumour or intramuscular EndoC-βH1 transplants. Ex vivo biodistribution analysis of radiolabelled 4hD29 or control (non-specific) nanobody (BcII10) was performed in mice xenografted with Kelly neuroblastoma cells (n = 4) (A,C–E) or with EndoC-βH1 transplants (n = 5) (B,F–H). The evaluation was done 60 or 80 minutes, respectively, after i.v. administration of 5 µg ^99mTc-labelled nanobody 4hD29 (white bars) or control nanobody BcII10 (black bars) and expressed as percent of injected activity per gram of tissue (%IA/g) ± SEM; (C,F) Individual uptake levels of tracers in Kelly tumours (C) or EndoC-βH1 transplants (F). Tumour-to-blood (D,G) and tumour-to-muscle ratios (E,H) of individual mice with either Kelly tumours (D,E) or EndoC-βH1 transplants (G,H). Data is presented as mean ± SEM; unpaired t-test, *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001.