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. 2017 Nov 9;7:15208. doi: 10.1038/s41598-017-15207-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Increased expression of pAKT protein in human AAA. (A) Representative human aortic histology images for pAKT staining. Original magnification: ×20 and ×100. (B) pAKT⁺ cells in media and adventitia were counted on each HPF (100×), and data present as mean and SD per HPF. n = 24 for aneurysm group and n = 6 for normal aorta group. Nonparametric Mann-Whitney test. *P < 0.05 vs aneurysm group. (C) Protein levels of pAKT in human aneurismal tissues and normal aorta tissues were determined by Western Blot. Ao is representative for aorta and An is representative for aneurysm. Original uncropped western blots are provided in a Supplementary Figure 1. Data present as mean and SD, n = 24 for aneurysm group and n = 6 for normal aorta group. Nonparametric Mann-Whitney test. *P < 0.05 vs aneurysm group. HPF, High-power field.