Table 3.

Prospective studies evaluating early detection and treatment to reduce rates of chronic BCRL

Institution	Year published	Number of patients	Measurement technique	Treatment	Results
University of Queensland	2002	65	Circumference + BIS	Physiotherapy vs. standard follow-up	Physiotherapy reduced BCRL at two years (11 vs. 30%)
National Naval Medical Center	2008	196	Perometry	Compression garment with detection	Only 6% of patients developed chronic BCRL
Alcala de Henares University	2010	120	Circumference	Physiotherapy vs. education	Physiotherapy reduced BCRL at one year (7 vs. 25%)
University of Pittsburgh Medical Center	2014	186	BIS	Compression garment with detection	Clinical BCRL 4.4% with BIS vs. 36.4% with circumferential measurement follow-up