Table 3.
Trial | N | Stage 1–3 | Stage 4S | Stage 4 and aged <18 mo | Stages 1–3/4S/4 aged <18 mo | Stage 4 and aged ≥18 mo | All | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n/N | % | n/N | % | n/N | % | n/N | % | n/N | % | n/N | % | ||
NB90 | 630 | 30/301 | 10.0 | 8/62 | 12.9 | 25/65 | 38.5 | 63/428 | 14.7 | 60/202 | 29.7 | 123/630 | 19.5 |
NB97 | 1174 | 56/684 | 8.2 | 10/111 | 9.0 | 41/101 | 40.6 | 107/896 | 11.9 | 75/278 | 27.0 | 182/1174 | 15.5 |
NB2004 | 1447 | 59/714 | 8.2 | 21/175 | 12.0 | 52/130 | 40.0 | 132/1019 | 13.0 | 150/428 | 35.0 | 282/1447 | 19.5 |
All | 3251 | 145/1699 | 8.5 | 39/348 | 11.2 | 118/296 | 39.9 | 302/2343 | 12.9 | 285/909 | 31.3 | 587/3251 | 18.1 |
n number of patients with MYCN amplification per group, N number of patients per group (stage, age)
a MYCN data missing in additional 398 patients (10.9%)