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. 2017 Aug 7;19(6):577–593. doi: 10.1007/s40272-017-0251-3

Table 3.

Frequencies of MYCN amplification in 3251 patients with neuroblastomaa by trial

Trial N Stage 1–3 Stage 4S Stage 4 and aged <18 mo Stages 1–3/4S/4 aged <18 mo Stage 4 and aged ≥18 mo All
n/N % n/N % n/N % n/N % n/N % n/N %
NB90 630 30/301 10.0 8/62 12.9 25/65 38.5 63/428 14.7 60/202 29.7 123/630 19.5
NB97 1174 56/684 8.2 10/111 9.0 41/101 40.6 107/896 11.9 75/278 27.0 182/1174 15.5
NB2004 1447 59/714 8.2 21/175 12.0 52/130 40.0 132/1019 13.0 150/428 35.0 282/1447 19.5
All 3251 145/1699 8.5 39/348 11.2 118/296 39.9 302/2343 12.9 285/909 31.3 587/3251 18.1

n number of patients with MYCN amplification per group, N number of patients per group (stage, age)

a MYCN data missing in additional 398 patients (10.9%)