Figure 2.

Proposed mode of action of the chlorite-based drug solution WF10 in hyperglycemic patients. Red blood cells of these patients are prone to hemolysis. Hemoglobin might be released from deformed, osmotically instable cells. A second hemolytic mechanism is mediated by hemin, a highly toxic hemolysis product, which can accumulate after exhaustion of the natural protecting serum proteins haptoglobin and hemopexin. WF10 prevents hemolysis events by inactivation of hemoglobin and oxidized hemoglobin forms and induces a removal of pre-damaged red blood cells.