Table 5. Survival outcomes by combining mrTRG and pTRG.
| Outcome measure | pTRG/mrTRG subgroup | n Events/n subjects | 5-year survival (95% CI) | Hazard ratio (95% CI) | P value |
|---|---|---|---|---|---|
| RFS | pTRG 0–1/mrTRG any pTRG 2/mrTRG 3–5 | 40/96 | 62.7 (52.9–72.5) | 1.0 | 0.001 |
| pTRG 2/mrTRG 1–2 pTRG 3–4/mrTRG any | 17/95 | 86.0 (78.9–93.1) | 0.37 (0.21–0.66) | ||
| OS | pTRG 0–1/mrTRG any pTRG 2/mrTRG 3–5 | 36/96 | 67.5 (57.9–77.1) | 1.0 | 0.003 |
| pTRG 2/mrTRG 1–2 pTRG 3–4/mrTRG any | 15/95 | 88.1 (81.4–94.8) | 0.39 (0.22–0.72) |
Abbreviations: CI=confidence interval; mrTRG=magnetic resonance tumour regression grade; OS=overall survival; pTRG=pathological tumour regression grade; RFS=recurrence-free survival.