Fig. 3.

Increased ROS production and decreased GSH levels in PSP-MSCs. Representative traces for the rate of mitochondrial reactive oxygen species (ROS) generation (A.) and quantification of these experiments (A1.) in patient (light green, green, olive) and control (black, dark grey) MSCs. B. Representative images of control and patient MSCs, labeled with MitoTracker Red CM-H2XROS. B1. Levels of Glutathione (GSH), assessed by MCB fluorescence- controls (black, dark grey) and patient MSCs (teal). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)