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. 2017 Oct 26;9(10):2190–2208. doi: 10.18632/aging.101308

Figure 2. Aging is associated with cortical porosities, regional variation in mineral density and growth plate closure.

Figure 2

(A) microCT reconstruction of distal femur cortical bone in an aged female showing cortical porosity (arrow). (B) BSEM image of the distal femur (Bar = 500μm) and midshaft cortical bone (Bar = 50μm) in young and aged C57BL/6 mice. Arrow indicates growth plate closure in the aged male and * indicates cortical porosities. (C) Quantitation of cortical porosity from n=5 animals showing a significant increase in cortical porosity in female C57BL/6 mice with age.