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. 2017 Oct 5;8(10):e3065. doi: 10.1038/cddis.2017.451

Table 1. Parameters evaluated in animals involved in the study.

  Water-drinking rats
Caffeine-drinking rats
  Basal 2 weeks treatment 3 weeks treatment Basal 2 weeks treatment 3 weeks treatment
Fluid intake (ml per day)   36±3 31±4   30±2 28±1
Caffeine consumption (mg/kg per day)         125±7 110±9
Serum caffeine (μM)         54.6±20.5 97.5±10.7
Retinal caffeine/pentoxifylline (ng/mg prot)         277±25 189±26
IOP (mmHg) 11±0.2 12±0.5 12±0.8 12±0.4 12±0.3 12±1.0

Abbreviation: IOP, intraocular pressure.