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The dynamic changes in HBV DNA levels and HBV DNA undetectable rates. HBV DNA levels (A) were decreased significantly at week 12 and maintain at low levels after week 12 in four group patients, while LMV group were increased slightly at week 48 because of viral breakthrough. Cumulative incidence of patients with undetectable serum HBV DNA rates (B) were also increased significantly at week 12 in four groups patients, especially in ETV group.
