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. 2017 Sep 21;14(6):6387–6394. doi: 10.3892/ol.2017.7010

Figure 5.

Figure 5.

Curcumol triggered activation of the JNK signaling pathway. (A) Western blot analysis of p-JNK and t-JNK in MG-63 cells treated with curcumol 63.5 mg/l for 24, 48 and 72 h. GAPDH served as the loading control. (B) Densitometric analysis of p-JNK and t-JNK. (C) Western blot analysis of LC3II/LC3I and p-JNK protein levels. MG-63 cells were treated with curcumol (63.5 mg/l) for 48 h in the presence or absence of SP600125 (20 µM). (D) Densitometric analysis of LC3II/LC3I, p-JNK protein levels with or without SP600125. #P<0.05 compared with the control group; *P<0.05 compared with the curcumol treatment group. JNK, Janus kinase; p-, phosphorylation, t-, total; LC3, light chain 3; cur, curcumol; SP, SP600125.