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Frax-1036 and Rottlerin co-administration synergizes the inhibition of OVCAR-3 cell line growth (A) and colony formation (B). Frax-1036 and Rottlerin synergistically inhibit phosphorylation of critical signaling molecules such as Mek, Erk1/2, β-catenin, and 4EBP1 (C)
