Table 2.

Analysis of differentially expressed genes related to pigmentation

Gene	RCC_FPKM	WCC_FPKM	P_value	Note
Wnt2b	1.112	4.019	3.00E-50	Wnt family member 2b
Pax3a	0.853	8.546	4.00E-18	Paired box protein Pax-3a
Mitfa	0.647	2.645	1.00E-59	Microphthalmia associated transcription factor a
Foxd3	10.032	1.257	0	Forkhead box D3
Tyr	1.094	2.456	0	Tyrosinase
Tyrp1b	0.435	2.992	0	Tyrosinase-related protein 1b
Dct	0.214	2.124	2.00E-92	Dopachrome tautomerase
Silva	0.684	3.794	2.00E-113	Silver protien a
Hpda	103.485	37.312	1.00E-139	4-hydroxyphenylpyruvate dioxygenase a
Mc1r	0.863	2.111	2.00E-27	Melanocortin receptor 1
Hgd	14.715	5.784	2.00E-87	Homogentisate1,2-dioxygenase
Gch1	4.461	2.152	7.00E-23	GTP cyclohydrolase 1
Xdh	6.877	2.571	0	Xanthine dehydrogenase/oxidase
Kitla	5.989	2.667	0	Kit ligand a
Ptps	6.028	0.547	6.00E-120	6-pyruvoyl tetrahydropterin synthase
Atg4a	1.311	0.214	0	Autophagy related 4 homolog A
Atg9a	9.862	4.478	0	Autophagy related 9 homolog A
Tfe3a	9.802	4.732	1.00E-23	Transcription factor binding to IGHM enhancer 3a
C-fos	7.477	63.901	7.00E-99	C-Fos protein
Gnas	2.457	5.253	1.00E-07	Guanine nucleotide-binding protein G(s) alpha
Gch2	1.194	9.245	5.00E-172	GTP cyclohydrolase 2
Tp53	3.013	1.717	0	Tumor protein p53
Chuk	3.993	8.183	1E-136	Inhibitor of nuclear factor kappa-B kinase alpha
Il3ra	5.661	0.692	7.00E-14	Interleukin 3 receptor alpha
Il1r1	7.693	1.916	3.00E-177	Interleukin 1 receptor type I
Il-8	13.218	6.084	2.00E-26	Interleukin-8
C-fms	6.907	1.148	0	Colony stimulating factor 1 receptor
Pax6b	3.518	0.922	1.00E-50	Paired box protein Pax-6b
Tsc1a	14.976	3.016	0	Tuberous sclerosis 1a
Sox9b	4.202	2.215	9.00E-169	HMG-box transcription factor Sox9b
Erk2	2.078	4.178	0	Extracellular signal regulated protein kinase 2