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. 2017 Nov 9;12:169. doi: 10.1186/s13018-017-0669-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Representative histologic sections (Safranin O/Fast Green stain) of the disc and endplate (original magnification, ×10). a Young group. b Middle-aged group. c Old group. With aging, the concentration of sulfated glycosaminoglycans (sGAG, arrows) was decreased and resorption of the articular cartilage was replaced by bone in the endplate