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. 2017 Nov 9;18:854. doi: 10.1186/s12864-017-4236-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Proposed coordinated process of myocyte reprogramming. Reprogramming “post-mitotic” myocytes into dedifferentiated myoblasts would require a complex, temporally sensitive, orchestration of genes and pathways involved in the regulation of chromatin modifications, protein degradation, RNA processing, and DNA and protein synthesis.