Figure 2.

Storage stability of MP0250 assessed by reverse-phase HPLC analysis. MP0250 at ∼ 15 mg/mL in PBS was stored for up to 24 months at −70°C (open circles), −20°C (open squares), 5°C (open triangles), or 25°C (open diamonds) in glass vials. Reverse-phase HPLC (see Materials & Methods) was used to determine the % of main peak at 1, 2, 3, 6, 9, 12, 18, or 24 months of incubation. In frozen state at −70°C and −20°C, the % main peak value in reverse-phase HPLC is stable with only minor change. Similarly, the % main peak value for MP0250 stored at +5°C is stable with only minor change over the time measured. As expected, a decrease in % of main peak was observed when MP0250 was incubated at +25°C for several months.