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. 2017 Aug 16;9(8):1231–1252. doi: 10.1080/19420862.2017.1367074

Figure 8.

Figure 8.

Immunofluorescence patterns of V-region identical chimeric mAbs binding to encapsulated Cryptococcus neoformans cells. Differences in the fluorescence pattern and intensity throughout the capsule are observed: IgG1, IgG2, IgG4, and IgA1 produced an annular pattern, whereas IgG3 and IgM revealed a punctate pattern. IgG4 gave a thick annular pattern that is different from the other subclasses. Figure reproduced from124 with permission from Copyright 2002. The American Association of Immunologists, Inc.