Table 2.
Participants’ characteristics and univariable logistic regression of the association between mild flu and rs12252 polymorphisms, BMI, diabetes, and hypercholesterolemia in an Iranian sample with Fars ethnic background
| Variables | Case | Control | OR | 95% CI | P value |
|---|---|---|---|---|---|
| n = 79 | n = 125 | ||||
| Age (mean ± SD) | 46.46 ± 22.90 | 50.62 ± 25.30 | 0.99 | 0.98, 1.00 | 0.275 |
| BMI (mean ± SD) | 26.51 ± 8.67 | 23.76 ± 4.67 | 1.06 | 1.01, 1.13 | 0.034 |
| Province n (%) | |||||
| Semnan | 36 (45.57) | 91 (72.80) | 0.36 | 0.13, 0.95 | 0.039 |
| Markazi | 33 (41.77) | 25 (20.00) | 1.19 | 0.42, 3.36 | 0.745 |
| Zanjan | 10 (12.66) | 9 (7.20) | 1 | – | – |
| Hypercholesterolemia n (%) | |||||
| Positive | 3 (3.80) | 16 (12.80) | 0.27 | 0.08, 0.96 | 0.042 |
| Negative | 76 (96.20) | 109 (87.20) | 1 | – | – |
| Diabetes n (%) | |||||
| Positive | 12 (15.19) | 42 (33.60) | 0.35 | 0.17, 0.73 | 0.005 |
| Negative | 67 (84.81) | 83 (66.40) | 1 | – | – |
| Genotype n (%) | |||||
| CC | 3 (3.80) | 1 (0.80) | 5.37 | 0.55, 52.68 | 0.149 |
| TC | 9 (11.39) | 4 (3.20) | 4.03 | 1.20, 13.58 | 0.025 |
| CC + CT | 12 (15.19) | 5 (4.00) | 4.29 | 1.45, 12.72 | 0.008 |
| TT | 67 (84.81) | 120 (96.00) | 1 | – | – |
| Allele n (%) | |||||
| C allele | 15 (9.49) | 6 (2.40) | 4.26 | 1.51, 13.67 | 0.0016 |
| T allele | 143 (90.51) | 244 (97.60) | 1 | – | – |