Table 3.
IFITM3 rs12252 genotype frequencies among mild flu cases and flu-negative controls, based on participants’ province of residence
| Genotype | HWE | ||||||
|---|---|---|---|---|---|---|---|
| CC | TC | TT | P valuea* | P valueb* | X2 | P value | |
| Total | 0.120 | 0.926 | – | – | |||
| Province | |||||||
| Zanjan | 0 | 1 | 18 | ||||
| Semnan | 1 | 11 | 115 | ||||
| Markazi | 3 | 1 | 54 | ||||
| Cases | 0.63 | > 0.05 | |||||
| Province | 0.073 | 0.099 | – | – | |||
| Zanjan | 0 | 0 | 10 | ||||
| Semnan | 1 | 8 | 27 | ||||
| Markazi | 2 | 1 | 30 | ||||
| Controls | 0.03 | > 0.05 | |||||
| Province | 0.185 | 0.361 | – | – | |||
| Zanjan | 0 | 1 | 8 | ||||
| Semnan | 0 | 3 | 88 | ||||
| Markazi | 1 | 0 | 24 | ||||
HWE Hardy Weinberg Equilibrium
*Fisher’s exact test
aAssociation analyses are performed based on codominant genetic model (CC, TC, and TT)
bAssociation analyses are performed based on dominant genetic model (CT + CC vs. TT)