Table 3.

Additional serological findings possible in PSC

Serologic finding	Prevalence
Hypergammaglobulinemia	30%
Increased serum immunoglobulin M (IgM) levels	40–50%
Atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA)	30–80%
Human leukocyte antigen DRw52a	0–100% in various reports
Increased immunoglobulin G4 (IgG4)	9%

Note: Data from Pollock et al.13

Abbreviation: PSC, primary sclerosing cholangitis.