Table 2.
Significant associations between the methylation of specific CpG sites in umbilical cord at birth with doctor diagnosed asthma at ages 3 and 6-7 years (* denotes p<0.05).
CpG | Genomic coordinates | Median ratio at age 3 years (yes/no)(N cases/ N controls) |
P value |
---|---|---|---|
GATA3 CpG -2211/-2209 | chr10:8134451,53+ | 0.737 (31/500) | 0.006* |
Median ratio at age 6-7 years (yes/no)(N cases/ N controls) |
|||
GATA3 CpG -2211/-2209 | chr10:8134451,53+ | 0.895 (79/475) | 0.048* |
IL-4R CpG +28239 | chr16:27260974+ | 0.98 (15/85) | 0.029* |