. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: Clin Exp Allergy. 2017 Aug 31;47(12):1599–1608. doi: 10.1111/cea.12988

Table 3.

Significant associations found between the methylation of specific CpG sites in umbilical cord at birth with atopic eczema at 12 months of age (* denotes p<0.05).

CpG	Genomic coordinate	Median ratio at age 12 months (yes/no) (N cases/ N controls)	P value
GATA3 CpG -2145/-2143	chr10:8134517,19+	1.20 (67/575)	0.054
IL-4R CpG +28239	chr16:27260974+	1.02 (13/87)	0.028*
IL-4R CpG +28269	chr16:27261004+	1.03 (13/81)	0.059
STAT4 CpG -229	chr2:191724460-	0.981 (19/154)	0.067

		Median ratio at age 6-7 years (yes/no)
IL-4 CpG -9664	chr5:132027913+	1.02 (15/104)	0.0498*