Figure 7.

bFKB1 reduces sweet-food and alcohol preference. (A) Body weight, (B) total food consumption, and (C) % Saccharin-containing food consumption pre- and post-antibody injection. Mice were given access to both control chow and saccharin-containing chow. The indicated antibody was administered on day 0 and 17 at 10 mg/kg each time (arrows). (D) % Alcohol-containing water consumption pre- and post-antibody injection. Mice were given access to two water bottles, one containing regular water and the other containing 4 or 12% ethanol in water. After acclimation to alcohol, mice were injected with 10 mg/kg of the indicated antibody on day 0 (arrow). (E) % body weight change between IgG vs bFKB1 treated mice in the alcohol preference study on day 21. Data are mean ± SEM. p < 0.05 (*), <0.01 (**), <0.001 (***) vs control.