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. 2017 May 25;25(7):1093–1096. doi: 10.1016/j.jsps.2017.05.005

Table 3.

Response of CPs to use of over-the-counter (OTC) medications during pregnancy.

Medication Not Safe in the first trimester Must weigh risks and benefits for individual patients Safe in the first trimester I don’t know
N (%) N (%) N (%)
Acetaminophen 2 (0.8) 9 (3.5) 237 (92.6) 8 (3.1)
Aspirin 7 (2.7) 141 (55.1) 94 (36.7) 14 (5.5)
Bismuth subsalicylate 120 (46.9) 71 (27.7) 53 (20.7) 12 (4.7)
Caffeine 16 (6.30 63 (24.6) 170 (66.4) 7 (39.0)
Dextromethorphan hydro bromide 11 (4.3) 66 (25.8) 137 (53.5) 39 (15.2)
Guaifenesin 42 (16.4) 33 (12.9) 164 (64.1) 17 (6.6)
St. John’s Wort 202 (78.9) 24 (9.4) 10 (3.9) 19 (7.4)
Ibuprofen 145 (56.6) 47 (18.4) 23 (9.0) 40 (15.6)
Pseudoephedrine hydrochloride 32 (12.5) 87 (34) 101 (39.5) 35 (13.7)
Supplement Vitamin A 124 (48.4) 46 (18) 15 (5.9) 67 (26.2)