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. Author manuscript; available in PMC: 2017 Nov 10.
Published in final edited form as: Jacobs J Diabetes Endocrinol. 2016 Oct 25;2(1):013.

Figure 1.

Figure 1

Hepatic expression of AMPK and pAMPKT172. (A) Western blot image of AMPK and pAMPKT172 in liver tissue lysates of each mouse group (normalized to total protein content derived from Ponceau S stain). (B) Densitometry analysis reveals significantly increased pAMPKT172 expression in MRL HFD with no significant changes on their B6 age-pair controls. (C) Densitometry analysis of AMPK reveals significantly increased AMPK in MRL vs B6, with the HFD-fed MRL group expressing a ~5-fold difference when compared with diet-matched B6. (D) Overall changes in the pAMPKT172/AMPK ratio, with both strains showing a marked difference against their diet-matched cohorts. n=5–6; * p <0.05, ** p<0.01. AMP dependent protein kinase (AMPK), phosphorylated AMPK (pAMPKT172).