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. Author manuscript; available in PMC: 2017 Nov 10.
Published in final edited form as: Jacobs J Diabetes Endocrinol. 2016 Oct 25;2(1):013.

Figure 7.

Figure 7

Akt was upregulated after a high-fat feeding protocol. Liver lysates were western blotted and assessed for protein kinase B (Akt) and pAktS473 levels. (A) Density of bands was taken and normalized against Ponceau S stained bands. (B) When compared to diet-matched control (B6 HFD), MRL mice show an increase in Akt-1 phosphorylation. (C) However, both strains show a significant decrease in basal Akt-1 after 12 weeks of diet intervention. (D) Overall, MRL mice subjected to HFD presented a greater ratio of phosphorylated: dephosphorylated Akt-1. n=3; each; * p <0.05, ** p<0.01