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. Author manuscript; available in PMC: 2017 Nov 10.
Published in final edited form as: IEEE Trans Biomed Eng. 2014 Apr 22;61(7):2199–2208. doi: 10.1109/TBME.2014.2319194

TABLE I.

Targets, Boundaries and Results of MOO and BF Methods

Acoustic variables Two layer VF Three layer VF
Target Min Max X from opt X from BF Target Min Max X from opt X from BF
F¯0 (Hz) 80 50 110 93 97 130 90 170 135 156
SPL¯ (dB) 110 90 130 no 110 70 50 90 78 81
μ2/μ1
N/A 0.05 20 0.8 (F¯0)
0.85 (SPL¯)
0.94 (F¯0)
1.24 (SPL¯)
N/A 0.05 20 0.85 (F¯0)
0.85 (SPL¯)
0.95 (SPL¯)
1.05 (F¯0)
μ3/μ2
N/A N/A N/A N/A N/A N/A 0.05 20 0.65 (SPL¯)
0.7 (F¯0)
0.8 (F¯0)
0.8 (SPL¯)

MOO was tested on two vocal fold designs. A two-layer vocal fold is based on morphological and mechanical data collected from tiger larynges and vocal folds [37], [31]. The three-layer vocal fold is based on human data from various sources [16]. The table lists two variables in the objective domain ( F¯0, SPL¯) and two translayer ratios of longitudinal shear modulus of different layers ( μ2/μ1 and μ3/μ2) implemented in the finite element model. VF-vocal fold, opt-NSGA-II optimization, BF-brute force, X-centroid of the highest density cluster for optimization and brute force method, respectively, and for ( F¯0) and ( SPL¯), respectively.