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Naïve T-cells can be used as cell carriers due to their organotropism. a) Naïve T-cells circulate throughout the body and are able to home to lymph nodes. b) Bioluminescence imaging of mice treated after 16 days. Naïve T-cells loaded with SN-38 lipid nanocapsules reduced tumor burden. c) Overall survival of mice treated with PBS, SN-38, SN-38 NC, and SN-38 NC conjugated to T-cells.
