Table 3.
Age-Adjusted and Multivariable Model Predictors of Improvement in Frailty Status from Visit 1 to Visit 2
| Prefrail to robust | Frail to prefrail or robust | |||
|---|---|---|---|---|
| Adjusted1 OR (95% CI) |
Multivariable OR (95% CI) |
Adjusted1 OR (95% CI) |
Multivariable OR (95% CI) |
|
| Albumin < 4 g/dL | – | – | 0.2 (0.1, 0.7) | 0.2 (0.1, 0.8) |
| IL-6 highest quartile | 0.3 (0.1, 0.7) | 0.3 (0.1, 0.7) | – | – |
| COPD | – | – | 0.3 (0.1, 0.7) | 0.3 (0.1, 0.9) |
| Diabetes Mellitus | – | – | 0.3 (0.1, 0.8) | 0.2 (0.1, 0.8) |
| Any IADL limitations | 0.4, (0.2, 0.5) | 0.5 (0.3, 0.8) | 0.3 (0.2, 0.6) | 0.4 (0.2, 0.8) |
| Leg power (W)2 | 1.6 (1.4, 1.8) | 1.5 (1.2, 1.7) | 2.1 (1.4, 3.1) | 2.0 (1.2, 3.3) |
| Married | 1.6 (1.1, 2.2) | 1.5 (1.02, 2.2) | 4.3 (1.9, 10.5) | 3.6 (1.1, 11.7) |
| Self-reported health (good/excellent) | 2.2 (1.5, 3.2) | 1.6 (1.03, 2.6) | – | – |
1
Adjusted for age and site
2
The effect estimates (ORs) for all continuous variables were expressed per standard deviation increment, except age, which was expressed per one-year increment. For continuous variables, odds ratios refer to increments of one standard deviation.
OR = odds ratio; COPD = chronic obstructive pulmonary disease; IADL = instrumental activities of daily living