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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Fungal Genet Biol. 2017 Sep 12;108:13–25. doi: 10.1016/j.fgb.2017.08.008

Fig. 6. Virulence of KN99mCH.

Fig. 6

A: Group of five mice (female CBA/J) were subjected to intranasal inoculation with 105 cells of the indicated strains and survival was followed by monitoring the body weight. Mice that lost 25% of their starting bodyweight were considered ill and were sacrificed. Data shown represent two independent experiments with KN99α and KN99mCH (p<0.05) and one for KN99G418. At the end point of survival experiment, organ homogenates were plated to calculate colony forming units for lung (B), brain (C) and spleen (D). No significant difference in the CFU between either KN99α or KN99mCH or KN99G418 after one-way ANOVA employing Dunnett’s multiple comparison test (GraphPad Prism Ver7).