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. Author manuscript; available in PMC: 2017 Nov 13.
Published in final edited form as: Leukemia. 2017 May 10;31(12):2661–2669. doi: 10.1038/leu.2017.141

Figure 8.

Figure 8

ELK1 and FOS are crucial factors for MM cell growth.

(a,b) MM.1S, RPMI 8226 and KMM-1 cells were transduced with shELK1, shFOS or shLuc. Three days post infection is designated as day 0. (a) On day 0, whole cell lysates were extracted and subjected to immunoblot analysis with anti-ELK1 or FOS. (b) The cell growth rate (day 5/day 0) relative to shLuc is shown. Data represent mean ± s.d. of quadruplicate cultures. *** P < 0.001 compared with shLuc.

(c) MM.1S cells transduced with shKDM6B or shLuc were treated with BMSC CM or control culture medium for 2h. Data represent the amount of mRNA relative to shLuc treated with control culture medium. Error bars indicate s.d. of triplicate measurements. *P < 0.05, ***P < 0.001.