Fig. 4.

Accuracy of the computer-based segmentations versus inter-operator variability of manual segmentation. The average accuracy of one set of 10 automatic and nine sets of 10 semi-automatic segmentations in comparison with three manual reference segmentations in terms of (a) MAD, (b) DSC, (c) recall, (d) precision, and (e) ΔV. The dashed line segments show the observed range of each metric at each ROI in pairwise comparison between three manual segmentations. For ΔV, the ranges are based on the absolute value of ΔV due to lack of reference in comparison of two manual segmentations. The error bars show one standard deviation. The significant differences detected between semi-automatic and automatic segmentation at different ROIs have been indicated on the graphs with an asterisk (p value < 0.05)