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. 2017 Nov 10;7:15244. doi: 10.1038/s41598-017-15456-9

Table 2.

Common stroke scale test and blood biomarker detection results.

Placebo group (n = 20) Treatment group (n = 22) Main effect of time Main effect of group Interaction
Baseline 2 weeks later Baseline 2 weeks later F value P value F value P value F value P value
NIHSS 5.85(3.28) 3.65(2.80) 6.64(3.09) 3.23(2.41) 0.079 0.780 0.079 0.780 5.402 0.026*
Barthel 68.50(26.01) 80.75(19.49) 66.82(26.07) 67.62(25.74) 0.563 0.458 0.026 0.872 1.661 0.205
mRS 2.80(1.28) 2.00(1.33) 3.18(1.18) 1.73(1.32) 2.069 0.159 0.043 0.837 4.038 0.052
SSQOL 147.35(41.47) 189.40(37.97) 125.05(43.63) 204.05(44.27) 1.466 0.234 0.024 0.877 9.755 0.003**
Infarct volume 43280.70 (26358.07) 48388.95 (29839.52) 41005.36 (20465.21) 38572.29 (20386.29) 1.470 0.212 0.039 0.845 1.365 0.250
Fibrinogen 2.83(0.50) 2.75(0.52) 3.26(0.99) 9.26(1.12) 0.116 0.736 2.506 0.122 0.042 0.838
Hematocrit 39.09(4.72) 39.54(4.53) 39.70(4.41) 38.53(3.54) 3.978 0.054 0.001 0.980 4.601 0.039*
Total cholesterol 5.00(1.39) 4.67(0.99) 4.64(1.22) 4.34(0.98) 2.222 0.145 2.205 0.333 0.02 0.888
Triglyceride 1.81(1.99) 1.92(1.97) 1.91(1.00) 1.85(0.95) 0.013 0.909 0.131 0.719 0.948 0.336
Low-density lipoprotein 3.00(0.90) 2.77(0.67) 2.76(0.96) 2.54(0.68) 0.900 0.349 1.572 0.218 0.005 0.942
High-density lipoprotein 1.41(0.57) 1.22(0.25) 1.10(0.20) 1.17(0.27) 2.406 0.129 4.081 0.051 2.056 0.160

Values are mean (SD) or number of patients. NIHSS: National Institute of Health Stroke Scale; mRS: Modified Rankin Scale; SSQOL: Stroke-Specific Quality of Life Scale; * P < 0.05, ** P < 0.01.