Table 1.

Patient clinicopathological characteristics and relationship with PKM2 expression.

Characteristics	N	Cirrhosis HCC		P value	N	Non-cirrhosis HCC		P value
		low	high			low	high
Gender
Female	32	18	14	0.808	27	19	8	0.763
Male	93	50	43		67	45	22
Age
<45	30	15	15	0.579	27	22	5	0.077
≥45	95	53	42		67	42	25
Tumor size (cm)
≤5	48	33	15	0.011	40	31	9	0.107
>5	77	35	42		54	33	21
AFP (ng/ml)
≤20	33	23	10	0.04	28	21	7	0.349
>20	92	45	47		66	43	23
HBsAg
Positive	110	61	49	0.521	57	39	18	0.622
Negative	15	7	8		37	25	12
Multiplicity
Single	82	49	33	0.097	59	40	19	0.938
Multiple (≥2)	43	19	24		35	24	11
Vascular invasion
Presence	67	28	39	0.002	52	29	23	0.004
Absence	58	40	18		42	35	7
Intrahepatic metastasis
Presence	59	21	38	<0.001	37	20	17	0.019
Absence	66	47	19		57	44	13
TNM stage
I/II	82	50	32	0.042	58	42	16	0.104
III/IV	43	18	25		36	22	14
Tumor Differentiation
poor	76	47	29	0.037	57	37	20	0.413
well	49	21	28		37	27	10

P-values * were calculated using a chi-square (χ²) test. *P < 0.05.