Table 2.
Univariate analysis of different prognostic variables in DSS and RFS of CL-HCC patients using the by Cox proportional hazard model Abbreviations: 95% CI = 95% confidence interval; HR = hazard ratio; TNM stage = tumour node metastasis; P-value < 0.05.
| Variables | DSS | RFS | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P value | HR | 95%CI | P value | |
| Sex | ||||||
| male/female | 1.038 | 0.406–2.652 | 0.938 | 0.994 | 0.387–2.557 | 0.990 |
| Age(years) | ||||||
| ≤50/>50 | 0.662 | 0.339–1.292 | 0.227 | 0.689 | 0.358–1.362 | 0.292 |
| AFP(ng/ml) | ||||||
| ≤20/>20 | 1.526 | 0.279–2.990 | 0.047 | 0.528 | 0.279–1.001 | 0.050 |
| HBsAg | ||||||
| yes/no | 0.761 | 0.252–2.297 | 0.628 | 0.737 | 0.243–2.234 | 0.059 |
| Tumor size(cm) | ||||||
| ≤5/>5 | 1.475 | 0.543–1.927 | 0.029 | 3.415 | 1.214–3.805 | 0.009 |
| Multiplicity | ||||||
| Single/multiple | 0.755 | 0.364–1.565 | 0.45 | 0.717 | 0.343–1.499 | 0.377 |
| Intrahepatic Metastasis | ||||||
| yes/no | 2.191 | 0.943–3.854 | 0.03 | 1.212 | 0.748–1.942 | 0.041 |
| TNM stage | ||||||
| (I/II)/(III/VI) | 2.857 | 1.084–7.531 | 0.034 | 3.380 | 1.269–9.003 | 0.015 |
| Vascular Invasion | ||||||
| yes/no | 2.481 | 1.099–5.602 | 0.029 | 2.323 | 1.002–5.383 | 0.049 |
| Tumor Differentiation | ||||||
| Poor/well | 1.753 | 0.910–2.356 | 0.031 | 1.203 | 1.215–1.781 | 0.019 |
| PKM2 expression | ||||||
| low/high | 2.240 | 1.091–4.597 | 0.028 | 2.537 | 1.106–4.965 | 0.028 |