Table 1.
Prevalence of renal dysfunction in RA patients after stratification according to age or sex (n = 1908)
| Total (n = 1908) | Age (years) | Female/male | ||||||
|---|---|---|---|---|---|---|---|---|
| < 50 (n = 281) | ≥ 50 and < 60 (n = 378) | ≥ 60 and < 70 (n = 611) | ≥ 70 and < 80 (n = 442) | ≥ 80 (n = 196) | Female (n = 1558) | Male (n = 350) | ||
| Absolute eGFR,a mean (SD) | 69.0 (20.7) | 88.3 (18.7) | 76.9 (17.7) | 69.9 (16.3) | 58.1 (16.6) | 47.4 (14.8) | 67.5 (20.2) | 75.2 (21.5) |
| eGFR ranges, patient number (%) | ||||||||
| ≥ 60 | 1263 (66.2) | 268 (95.4) | 320 (84.7) | 450 (73.6) | 189 (42.8) | 36 (18.4) | 987 (63.4) | 276 (78.9) |
| < 60 | 645 (33.8) | 13 (4.6) | 58 (15.3) | 161 (26.4) | 253 (57.2) | 160 (81.6) | 571 (36.6) | 74 (21.2) |
| ≥ 45 and < 60 | 412 (21.6) | 11 (3.9) | 47 (12.4) | 128 (20.9) | 158 (35.7) | 68 (34.7) | 360 (23.1) | 52 (14.9) |
| ≥ 30 and < 45 | 193 (10.1) | 2 (0.7) | 8 (2.1) | 30 (4.9) | 82 (18.6) | 71 (36.2) | 176 (11.3) | 17 (4.9) |
| ≥ 15 and < 30 | 37 (1.9) | 0 | 3 (0.8) | 3 (0.5) | 12 (2.7) | 19 (9.7) | 33 (2.1) | 4 (1.1) |
| < 15 | 3 (0.2) | 0 | 0 | 0 | 1 (0.2) | 2 (1.0) | 2 (0.1) | 1 (0.3) |
| BSA-indexed eGFR,a mean (SD) | 78.4 (21.8) | 96.4 (19.3) | 84.9 (19.4) | 79.7 (18.5) | 68.1 (18.9) | 58.8 (17.6) | 78.8 (22.1) | 76.4 (20.2) |
| eGFR ranges, patient number (%) | ||||||||
| ≥ 60 | 1553 (81.4) | 276 (98.2) | 347 (91.8) | 538 (88.1) | 297 (67.2) | 95 (48.5) | 1263 (81.1) | 290 (82.9) |
| < 60 | 355 (18.6) | 5 (1.8) | 31 (8.2) | 73 (11.9) | 145 (32.8) | 101 (51.5) | 295 (18.9) | 60 (17.1) |
| ≥ 45 and < 60 | 263 (13.8) | 4 (1.4) | 25 (6.6) | 61 (10.0) | 110 (24.9) | 63 (32.1) | 217 (13.9) | 46 (13.1) |
| ≥ 30 and < 45 | 74 (3.9) | 1 (0.4) | 4 (1.1) | 9 (1.5) | 32 (7.2) | 28 (14.3) | 63 (4.0) | 11 (3.1) |
| ≥ 15 and < 30 | 15 (0.8) | 0 | 2 (0.5) | 3 (0.5) | 2 (0.5) | 8 (4.1) | 13 (0.8) | 2 (0.6) |
| < 15 | 3 (0.2) | 0 | 0 | 0 | 1 (0.2) | 2 (1.0) | 2 (0.1) | 1 (0.3) |
RA rheumatoid arthritis, eGFR estimated glomerular filtration rate, BSA body surface area, SD standard deviation
aBSA-indexed eGFR was first calculated using the following equation: BSA-indexed eGFR (ml/min/1.73 m2) = 194 × (serum creatinine [mg/dl])−1.094 × (age)−0.287 × 0.739 (if female) and was then converted to an unindexed eGFR (an absolute eGFR) using each patient’s BSA. Absolute eGFR (ml/min) = eGFR × BSA / 1.73 m2. Two measurements of eGFR were taken over a 3-month interval for individual patients, and average values were used