Table 2.
Prevalence of renal dysfunction in RA patients after stratification according to the presence of albuminuria or hematuria (n = 1908)
| Total (n = 1908) | Urine albumin | Hematuria | |||
|---|---|---|---|---|---|
| < “2+” (n = 1753) | ≥ “2+” (n = 155) | Negative (n = 1765) | Positive (n = 143) | ||
| Absolute eGFR,a mean (SD) | 69.0 (20.7) | 70.0 (20.3) | 57.5 (21.8) | 69.6 (20.7) | 60.7 (17.9) |
| eGFR ranges, patient number (%) | |||||
| ≥ 60 | 1263 (66.2) | 1199 (68.4) | 64 (41.3) | 1189 (67.4) | 74 (51.7) |
| < 60 | 645 (33.8) | 554 (31.6) | 91 (58.7) | 576 (32.6) | 69 (48.3) |
| ≥ 45 and < 60 | 412 (21.6) | 375 (21.4) | 37 (23.9) | 372 (21.1) | 40 (28.0) |
| ≥ 30 and < 45 | 193 (10.1) | 149 (8.5) | 45 (29.0) | 170 (9.6) | 23 (16.1) |
| ≥ 15 and < 30 | 37 (1.9) | 29 (1.7) | 7 (4.5) | 32 (1.8) | 5 (3.5) |
| < 15 | 3 (0.2) | 1 (0.1) | 2 (1.3) | 2 (0.1) | 1 (0.7) |
| BSA-indexed eGFR,a mean (SD) | 78.4 (21.8) | 79.5 (21.3) | 65.5 (22.4) | 79.0 (21.8) | 70.2 (19.3) |
| eGFR ranges, patient number (%) | |||||
| ≥ 60 | 1553 (81.4) | 1468 (83.7) | 85 (54.8) | 1449 (82.1) | 104 (72.7) |
| < 60 | 355 (18.6) | 285 (16.3) | 70 (45.2) | 316 (17.9) | 39 (27.3) |
| ≥ 45 and < 60 | 263 (13.8) | 217 (12.4) | 46 (29.7) | 238 (13.5) | 25 (17.5) |
| ≥ 30 and < 45 | 74 (3.9) | 57 (3.3) | 17 (11.0) | 63 (3.6) | 11 (7.7) |
| ≥ 15 and < 30 | 15 (0.8) | 10 (0.6) | 5 (3.2) | 13 (0.7) | 2 (1.4) |
| < 15 | 3 (0.2) | 1 (0.1) | 2 (1.3) | 2 (0.1) | 1 (0.7) |
RA rheumatoid arthritis, eGFR estimated glomerular filtration rate, BSA body surface area, SD standard deviation
aBSA-indexed eGFR was first calculated using the following equation: BSA-indexed eGFR (ml/min/1.73 m2) = 194 × (serum creatinine [mg/dl])−1.094 × (age)−0.287 × 0.739 (if female) and was then converted to an unindexed eGFR (an absolute eGFR) using each patient’s BSA. Absolute eGFR (ml/min) = eGFR × BSA / 1.73 m2. Two measurements of eGFR were taken over a 3-month interval for individual patients, and average values were used