Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 10;7:15280. doi: 10.1038/s41598-017-15527-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Tregs in peripheral blood of chronic HBV-infected patients and healthy volunteers. (a) Direct ex vivo flow cytometry staining experiment from a representative chronic HBV patient using antibodies against CD4 and FoxP3. Cells were gated on lymphocyte on the basis of forward and side scatter properties. The isotype-matched antibodies were used as controls. Number indicates the percentage of cells in the indicated region. (b) Percentage of Tregs (CD4⁺FoxP3⁺T cells within CD4⁺T cell fraction) of distinct immune phase was determined by FACS staining of PBMC of 124 chronic HBV patients and 38 healthy volunteers. (c) Association between circulating Treg frequency and serum HBV DNA load, HBsAg titer, age or ALT levels in chronic HBV patients. IP, inflammatory phase. Error bars denote the mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001.