Table 1.
Healthy volunteers | Chronic HBV-infected patients | ||||
---|---|---|---|---|---|
Immune tolerance phase | Immune clearance phase | Low- replicative phase | HBeAg- negative hepatitis phase | ||
Number | 38 | 20 | 35 | 35 | 34 |
Age (years)* | 48.2 ± 12.4 | 34.8 ± 6.6&,$ | 35.1 ± 11.0£,¥ | 49.5 ± 10.0&,£ | 49.7 ± 12.1$,¥ |
Male** | 22 (78.6) | 9 (45%) | 28 (82.9) | 21 (58.3) | 29 (85.3) |
ALT (U/L)* | 27.1 ± 16.5 | 25.8 ± 7.80 | 321.9 ± 272.7 | 21.4 ± 6.8 | 313.9 ± 277.7 |
HBV DNA (log IU/mL)* | 7.48 ± 1.42 | 7.36 ± 1.28 | 3.52 ± 1.31 | 6.16 ± 1.55 | |
HbsAg (log IU/mL)* | 4.15 ± 0.81 | 3.47 ± 1.20 | 2.17 ± 1.14 | 2.85 ± 0.91 |
&,$,£,¥p < 0.05. *Mean ± SD; **no. (%).