TABLE 1.

Model parameters.

Significance		Fig 2	Fig 2 and 6	Fig 3	Fig 3 B	Fig 3C	Fig 4 A	Fig 4 B	Fig 4 C	Fig 4 D	Fig 5
		Fast onset activity	Spont.transition from bckg to seizure like activity	Series of epileptic spikes	Interictal spikes	Evolution of spike shape	Seizure-like activity	Seizure-like activity	Seizure-like activity	Seizure-like activity	Evolution of seizure patterns
Average synaptic contact x → x	CPP	80	80	110	110	110	90	50	65	110	75
	CPI1	20	20	40	20	40	22	400	80	40	22
	CI1I1	15	15	25	15	15	20	60	70	15	21
	CI1P	80	80	55	80	60	118	100	50	60	118
	CPI2	5	5	6	5	6	10	50	15	6	10
	CI2P	20	20	20	20	20	16.5	25	20	20	16.5
Constant or time-dependent parameter in GABA	αI1P	0.017	0.017	0.0015	0.0005	0.085	0.14	0.119	0.019	0.017	0.17
	αI1I1	0.007	0.007	0.0086	0.067	0.017	0.13	0.39	0.075	0.085	0.118
Mean PSP amplitude (AMPA, GABA a, s GABA a,f)	WAMPA; WGABAa,s; WGABAa,f					5; 50; 20
Kinetic of PSP(AMPA, GABA a, s GABA a,f)	1/τAMPA; 1/τGABAa,s; 1/τGABAa,f					180; 33; 220
Wave to pulse function in subpopulation x.	⊝P; $Q_{\mathrm{P}}^{max}$; rP					6; 8; 1.2
	⊝I1; $Q_{\mathrm{I}1}^{max}$; rI1					8; 4.8; 0.5
	⊝I2; $Q_{\mathrm{I}2}^{max}$; rI2					8; 4.4; 0.5