Table 2.
Variable | Value |
---|---|
N of cycles of AA, median (range) | 10 (1–35) |
Last PSA, median (range), n = 130 | 9.7 (0.0 to 2743.0) |
12 weeks PSA, median (range), n = 99 | 7.7 (0.0 to 900.0) |
12 weeks PSA decline, n (%), n = 99 | 49 (49.5) |
12 weeks ALT, median (range), n = 58 | 22 (88–215) |
12 weeks AST, median (range), n = 58 | 23 (9–150) |
Patients’ subjective impression on AA regimen, n = 108 (missing =27) | |
1 = greatly improved | 35 (32.4) |
2 = improved | 41 (37.9) |
3 = not changed | 26 (24.0) |
4 = worsened | 6 (5.5) |
Median follow-up time, month (IQR) | 13.6 (7–16) |
Death, n (%) | 33 (22.8) |
Progression, n (%) | 56 (38.6) |
Median PFS, month (95% CI) | 18.5 (16–20) |
Median OS, month (95% CI) | 26.5 (21–32) |
Abreviations: PSA prostate specific antigen, AA abiraterone acetate, ALT alanine aminotransferase, AST aspartate aminotransferase, PFS progression free survival, OS overall survival