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. 2017 Nov 10;17:751. doi: 10.1186/s12885-017-3722-6

Table 3.

Significant genetic associations with cardiometabolic candidate genes

Common Variants
Gene SNP ID MAF p-value FDR Model
Dyslipidemia EIF4B rs146008363 0.05 0.00018 0.180 DOM
OGFOD3 rs62079523 0.33 0.00032 0.180 DOM
Extreme phenotype BAD rs2286615 0.10 0.00034 0.200 DOM
FCRL3 rs2282284 0.03 0.00042 0.200 DOM
Common/Rare variants
Gene Rare (n) Common (n) p-value FDR
Extreme phenotype BAD 3 1 5.79x10-5 0.087
FCRL3 2 1 3.86x10-5 0.087
EIF4B 1 1 0.00010 0.100

MAF Minor allele frequency, DOM Dominant effect, Rare (n) Number of rare variants analyzed in the gene, Common (n) Number of common variants analyzed in the gene, Extreme phenotype Three and more cardiometabolic risk factor