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. 2017 Nov 10;19:249. doi: 10.1186/s13075-017-1459-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — a Kolmogorov-Smirnov (K-S) plots showing cumulative distribution of microRNA (miR) miR-103a-3p expression for healthy control subjects (HCs; open circles), patients with rheumatoid arthritis (RA; closed squares), and first-degree relatives (FDRs; open triangles). The distance between two distribution plots is represented by double arrows. K-S distance ≥ 0.5 was considered significant. b ROC curves (representing 1-specificity vs sensitivity values) for HCs, patients with RA, and FDRs, calculated using expression values of miR-103a-3p