Table 1.
Clinical characteristics of the study population
| Healthy control subjects (n = 12) | ACPA+/patients with RA (n = 18) | ACPA+/FDRs (n = 12) | |
|---|---|---|---|
| Age, years, median (range) | 40 (23–66) | 46.6 (29–70) | 33.65 (28–60) |
| Sex, female/male | 10/2 | 14/4 | 12/1 |
| Disease duration, years, median (range) | NA | 12.02 (0–35.6) | NA |
| CRP titer, median (range) | 3.35 (1.07 –9.25) | 6.91 (2–42.6) | 2.595 (1.01–15.9) |
| RF titer, IU/ml, median (range)ml | <20 | 321 (20–1540) | 34.9 (20–570) |
| Anti-CCP titer, median (range) | 1 (0.4–2.0) | 201 (19–289) | 114 (7–365) |
| BMI, kg/m2, median (range) | 29.54 (19.9–34.4) | 27.37 (20.4–39.6) | 26.09 (19.6–40.7) |
Abbreviations: ACPA Anticitrullinated protein antibodies, BMI Body mass index, Anti-CCP Anticyclic citrullinated protein antibodies, CRP C-reactive protein, FDR First-degree relative, RA Rheumatoid arthritis, RF Rheumatoid factor, NA Not applicable
All values are reported as median (range) unless otherwise indicated