Fig. 2.

Validation of the controlled dataset. Panel a shows a comparison of all correlations of in normal versus tumor (stage T3) where differences in correlation are represented by colors codes as shown at right. Left and right show the differences in a negative gene and a positive gene respectively. Panel b shows the distribution of correlations of a representative negative and positive gene. Panel c shows a representation of distributions for negative and the two types of positive genes (by noise addition or network injection). Genes are shown in the vertical axis whereas the density of the distribution is represented by colors across correlation levels in the horizontal axis. For example, low density regions of the distribution, typically at both tails, are represented in dark green whereas high density regions are shown in yellow and red, typically close to 0. The arrows point to visible changes between normal and tumor T3